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Computer models predict the risk of fracture in clinics, but research is already a step ahead by abandieri — last modified 2008-09-23 10:41
The University of Sheffield registered a clinical trial
The skeleton of the European Virtual Human is “made in Italy” by abandieri — last modified 2008-09-29 18:01
Sept 1st, 2008: the VPHOP integrated project officially started
The Virtual Physiological Human: Building a Framework for Computational Biomedicine by abandieri — last modified 2008-10-16 14:35
Two themed issues on The Virtual Physiological Human were recently published
“The future of MAF”: the day after by abandieri — last modified 2008-10-23 15:38
On October 10th, in Bologna, a meeting day entitled “The future of MAF” was held, focused on the Multimod Application Framework (MAF), an Open Source software which enables the rapid development of the applications for the so called “computer aided medicine”.
Knee Arthroplasty: From Early Intervention to Revision - An IMechE conference by abandieri — last modified 2008-10-23 16:52
Call for Papers!
@neurIST Open Symposium by abandieri — last modified 2008-10-24 15:24
All FP6 and FP7 VPH community projects were invited
VPHOP Presented at TCN CAE 2008 by abandieri — last modified 2008-11-06 14:49
The TCN CAE 2008 International Conference on Simulation Based Engineering and Sciences was held in Venice on 16-17 October 2008. This year an entire parallel session was dedicated to biomedical applications, and Marco Viceconti, coordinator of the VPHOP project, was selected as keynote speaker for that session.
VPHOP at Europe for Patients by abandieri — last modified 2008-11-05 15:04
Marco Viceconti, coordinator of the VPHOP integrated project, gave an invited talk at the “Europe for patients” conference, organised at the Institut Pasteur in Paris. Dr. Viceconti described the prospective that VPHOP research and technological develop is likely to open for patients affected by osteoporosis.
ICCB2009: Final call for Papers! by abandieri — last modified 2008-11-14 18:13
All aspects of computational bioengineering
Osteoporosis in the European Union in 2008 by abandieri — last modified 2008-11-25 15:22
Ten years of progress and ongoing challenges. A decade after the landmark 1998 report and recommendations by the European Commission and as a comparison to the 2001 EU 'audit' report, this work, published in October 2008, provides a snapshot of the progress and challenges in osteoporosis management in the EU.
Stand Tall - Speak out for your bones by abandieri — last modified 2008-11-25 16:48
The two-year World Osteoporosis Day campaign aims at encouraging the global osteoporosis movement to mobilize public opinion to generate change in osteoporosis healthcare policies.
European prize awarded for 3D patient modeling by abandieri — last modified 2008-11-27 16:50
Professor Nicholas Ayache, a scientific pioneer in computational medical image analysis, was awarded one of the largest international prizes in science
IUPS nominates its next President by abandieri — last modified 2008-11-27 17:23
2009-2013: Professor Denis Noble, President of the International Union of Physiological Sciences (IUPS)
VPH Concertation Day Report - Published by abandieri — last modified 2008-12-01 10:06
Now available the report of the Concertation Meeting which gave the representatives from EC-projects - funded within the Seventh Framework (FP7) VPH Initiative, and VPH-related projects funded during Framework Six (FP6) - the first opportunity to gather and discuss about future multidisciplinary collaboration between the ICT and life sciences research communities.
VPHOP participate to the VPH Concertation Meeting by abandieri — last modified 2008-12-01 14:31
Representatives of the 15 research projects funded in the second call of FP7 under the topic “Virtual Physiological Human” met in Brussels on 22nd October 2008 in the so-called VPH Concertation Meeting. The meeting proposed by the e-health unit of the DG INFSO, which is in charge of the VPH projects, was intended as an opportunity for exchanging perspectives, agree on common goals, and identify possible collective actions. The workgroups conclusions suggest that a significant coordination work is required.
VPHOP at the ICT-BIO 2008 conference by abandieri — last modified 2008-12-01 16:28
As part of the ICT-BIO 2008 conference, the VPHOP consortium organised a session on the musculoskeletal system that showcased the state of the art in integrative biomedical research worldwide with respect to this important part of human pathophysiology. Speakers from Europe, Japan and United States presented very exciting developments such as the use of the Petaflop Japanese supercomputer, capable of 1000 billion operation every second, to simulate the human skeleton at an unsurpassed level of detail, or the prediction of neuromuscular control the astronauts will use while walking on Mars.
New FP7 calls on the Virtual Physiological Human presented at ICT2008 by abandieri — last modified 2008-12-10 17:09
After the great attention drawn in Helsinki on 2006, the Virtual Physiological Human (VPH) initiative kept a central place also at ICT2008, the biannual event that showcase the most important research activities supported under the Information and Communication Technology (ICT) programme of the Seventh Framework Program of the European Commission. The event gave the opportunity to the eHealth unit to present two new calls for proposals related to the VPH.
Building the Virtual Physiological Human Community by abandieri — last modified 2009-10-14 14:33
July 26th, 2009.The VPH Network of Excellence will host a Satellite Symposium at the XXXVI International Congress of Physiological Sciences in conjunction with Akinori Noma’s team at Ritsumeikan University.
Logo_iups_noe by Debora Testi — last modified 2008-12-23 19:43
Osteopenia vs Fall: the debate sparkles, confirming the VPH vision on osteoporosis research. by abandieri — last modified 2009-01-05 15:10
Letter on BMJ stresses the need of shifting the focus in fracture prevention from osteoporosis to falls, confirming the validity of the research and technological development objectives set for the VPHOP European research project.
VPHOP is presented at the VPH Industry day by abandieri — last modified 2009-02-04 17:50
The European Bioinformatics Institute, on behalf of the VPH Network of Excellence organised a two days meeting in Cambridge (UK) to present to the European industrial researchers the VPH initiative and its early results.
Stroetmann joins Healthcare IT Management by Martina Contin — last modified 2009-02-26 16:01
VPHOP consortium congratules with Karl Stroetmann, one of its principal investigators, for becoming member of Healthcare It Management's Editorial Board
Peter Hunter wins the New Zeeland Awards by Martina Contin — last modified 2009-03-12 09:59
Among New Zeeland's best talents, Peter Hunter receives a World Class New Zeeland Award in the category: Research, Science, Technology & Academia.
New evidence confirms osteoporosis is a rising healthcare risk by Martina Contin — last modified 2009-03-19 15:14
New evidence from the USA confirms osteoporosis is a major health treat causing millions of fractures each year with profound impact on quality of life and the economy, and calls for rapid advancement of innovative medical research
Bilateral fatigue fracture at 61 years old: a case report by Martina Contin — last modified 2009-03-23 15:40
A paper recently published on Orthopaedics by a group of clinicians at the University of Yamanashi reports the case of a 61 years old lady with a bilateral non-displaced fatigue fracture of the femoral neck.
No association between hip geometry and genes by Martina Contin — last modified 2009-03-17 15:13
A paper recently published on Calcified International by a group of researchers at the University of Southern Denmark shows that the geometric dimensions of the proximal femur in perimenopausal women are not associated with four polymorphisms in genes known to correlate with increased fracture incidence and/or reduced bone mineral density (BMD). The genetic contribution to the risk of osteoporosis does not seem to be mediated by the anatomic risk factors.
Principal Investigators Forum (VPHOP members only) by Martina Contin — last modified 2009-04-27 16:27
A Principal Investigators forum has been created to implement the communication between the PMO and the 19 partners of the VPHOP Consortium
Biannual Updates of the VPHOP Project Directory (VPHOP members only) by Martina Contin — last modified 2009-04-28 17:14
Principal Investigators will give their contribution to keep the Project Directory up to date.
ANSYS gets press coverage thanks to the VPHOP project by Martina Contin — last modified 2009-04-24 10:34
Ansys, the global innovator of simulation software and technologies, offers its contribute to the osteopororis fight generating interest on the press
VPHOP at the Infinity Initiative BioICT - The Heart in the Computer in Sophia Antipolis by Martina Contin — last modified 2009-04-24 10:33
Member of the VPHOP consortium Karl A. Stroetmann gave an invited expert presentation on the vision and clinical potentials of VPH during a series of advanced seminars about ‘Bio ICT-The Heart in the Computer’, organised at ETSI in Sophia Antipolis, France. Delegates included leading scientists and important industry leaders, EC decision-makers and major players in the field.
Download "Virtual Physiological Human Projects Portfolio" by Martina Contin — last modified 2009-05-05 10:53
On the eHealthNews website is now available the PDF version of a resource book with an overview of the set of Virtual Physiological Human (VPH)
European Commission proposes a new strategy for Europe’s global leadership in ICT by Martina Contin — last modified 2009-04-27 16:31
In a new strategy for ICT research and development, the European Commission (EC) underlines that industrial and technological leadership can be accelerated through supporting European-scale projects, such as R&D for innovative solutions for healthcare.
European Commission quotes Virtual Physiological Human a flagship research initiative for boosting Europe’s technological competitiveness by Martina Contin — last modified 2009-05-05 10:31
A new European plan promoting visionary research was unveiled by the European Commission to identify and launch new Future and Emerging Technology (FET) research flagship initiatives. According to the plan, initiatives like the Virtual Physiological Human exhibit the potential to address today’s socio-economic challenges and gain technologically competitive advantages for Europe.
The Project Board approves the Gantt Chart implemented by the Project Manager (VPHOP members only) by Martina Contin — last modified 2009-05-05 10:45
The final version of the Gantt chart is now available for the Consortium Partners to view. The Gantt Chart has been implemented by the Project Manager and formally approved during the last Project Board held in Munich in date 10/03/2009.
VPHOP adopts Extreme Project Management by Martina Contin — last modified 2009-05-12 12:34
The innovative project management model XPM is now fully operational to support the VPHOP classical project management.
VPHOP Coordinator leads EU scientific delegation at V-Tissues 2009 conference by Martina Contin — last modified 2009-05-20 11:40
The VPHOP Coordinator, Marco Viceconti co-chaired the Virtual Tissues 2009 conference, organised by the US Environmental Protection Agency in collaboration with the European Commission.
VPH in the context of Future and Emerging Technologies by Martina Contin — last modified 2009-05-20 12:33
VPHOP experts present The Virtual Physiological Human to the FET team
VPHOP showcased at Philips Research by Martina Contin — last modified 2009-05-26 11:36
The coordinator of the VPHOP project was invited in Aachen (DE) to give a presentation on multiscale modelling of the skeletal system to the staff of Philips Research. The conference was broadcasted to all Philips research sites around the world. The visit was also an opportunity to exchange experiences and ideas with colleagues and to learn more about VPHOP twin project Eu-Heart, which is applying the very same approach to cardiac pathologies.
VPHOP presented at R&D division of ESAOTE by Martina Contin — last modified 2009-05-22 11:45
VPHOP coordinator gave an invited talk to the R&D staff of ESAOTE entitled: “Toward a personalised, predictive, and integrative medicine: the VPHOP project”. The presentation was organised at the company headquarters in Genova (IT), and gave the opportunity to ESAOTE researchers to discuss with Dr. Viceconti the new opportunities that integrative research and multiscale modelling can provide to medical imaging technologies.
VPHOP presented at the Italian Institute of Technology by Martina Contin — last modified 2009-05-26 11:38
Marco Viceconti gave an invited lecture entitled “The Virtual Physiological Human: current status and perspectives” at the IIT. The seminar was organised by Giulio Sandini, Research Director of the Robotics, Brain & Cognitive Sciences area, by Darwin Caldwell, Research Director of the Advanced Robotics area, and by Pietro Morasso, Professor at the University of Genova, and Senior Researcher at the IIT.
Le LHDL est mort, vive le LHDL: VPHOP goes on PhysiomeSpace by Martina Contin — last modified 2009-05-26 11:37
The Living Human Digital Library, a FP6 project which aimed to develop a data-sharing infrastructure for integrative research, received during its final review meeting an “outstanding” evaluation by a panel of international experts, and was selected by the “ICT for Health” unit as “Project of Month”. The main project output, the PhysiomeSpace© data management & sharing service, will be used by the VPHOP project as infrastructure for secure data sharing between the four clinical centres, and the other 15 research institutions involved with the project.
Nicotine pathway on osteoblasts metabolism discovered by Martina Contin — last modified 2009-05-26 11:48
Israeli researchers founds that nicotine regulates the expression of various proteins linked to the proliferation and activity of osteblasts. This study provides a mechanistic basis to a number of phenomenological observations on the role of smoking as a major risk factor in bone diseases.
VPHOP completes a clinical study protocol for technology assessment by Martina Contin — last modified 2009-06-05 08:07
The technology leaders of VPHOP reached a key consensus with the project’s clinical partners about how to further develop and assess their simulation technologies. In a complex task consolidating the diverse research interests and resources of four large hospitals (Hôpitaux Universitaires de Genève, Switzerland; Charité - Universitätsmedizin Berlin, Germany; Istituti Ortopedici Rizzoli, Italy; and Institut National de la Santé et de la Recherche Médicale, France), a major milestone was accomplished by passing a central study protocol. The protocol defines how the clinical partners of the VPHOP consortium will collect and share clinical data that is necessary to perform the technology as well as the later socio-economic impact assessment
Automatic homepage for every BiomedTown citizen by Martina Contin — last modified 2009-06-04 10:18
A personal citizen homepage will now be available to improve the communication and the exchange of information among the BiomedTown population.
Empirica presents study results on global uptake of health ICT at OECD meeting by Martina Contin — last modified 2009-06-05 08:09
An OECD expert meeting was organised on May 25 on measuring the progress of global eHealth diffusion. VPHOP partner empirica presented results from two EC funded studies: eHealth Indicators - on the use of ICT by GPs in Europe and eHealth Benchmarking - a comprehensive inventory of available statistical evidence on eHealth in Europe, Canada and the USA. In many European countries, data showed that general practitioners extensively use ICT in their daily practice, and they are ready for using ever more advanced technologies.
VPHOP project presented at the IV Bone Quality Seminar 2009 by Martina Contin — last modified 2009-07-24 00:21
VPHOP coordinator was invited by the pharmaceutical company Servier to present the VPHOP project and its innovative multiscale personalized model for risk fracture prediction.
VPHOP presented at RIKEN Tokyo by Martina Contin — last modified 2009-07-16 17:45
RIKEN is one of the largest research organisations in Japan; its mission is to conduct comprehensive research in science and technology. One of the key targets of RIKEN is the development of multiscale models of human pathophysiology, also in relation to the development of the next-generation 10 petaflops Japanese supercomputer, for which RIKEN is responsible for the development, construction, and operation of the supercomputer, expected to be operational in 2012. In this context the mutual interest between RIKEN and VPHOP, the large European project on the multiscale modelling of the musculoskeletal system, comes quite natural. The visit of VPHOP Coordinator gave the opportunity to present latest results and future plans of the VPHOP project, and to learn more on the research activities being conducted at RIKEN in the area of virtual human.
VPHOP gets larger clinical support by Martina Contin — last modified 2009-07-23 23:25
Three illustrious clinicians have accepted to join the VPHOP clinical committee as external experts. The collaboration will offer to the European funded project the possibility to develop a technology which best suits the real needs of the clinical users.
VPHOP contributes to VPH NoE outreach event by Martina Contin — last modified 2009-09-28 14:15
The VPH NoE Network of Excellence organised in connection with the world congress of the International Union of Physiological Societies (IUPS) conference, a satellite symposium entitled “Building the Virtual Physiological Human Community. As part of the outreach initiatives of the European VPH action, the event saw the contribution, amongst others, from Marco ViceConti, coordinator of the VPHOP project, who co-chaired a round table on the pros and cons of public access to biomedical data and models.
The VPHOP consortium announces the results of the first project year by Martina Contin — last modified 2009-09-29 18:28
After only one year, the European investments for the fight against osteoporosis have already started to show their positive results. The VPHOP research project which successfully gained funding in 2008, celebrated a year of life and its remarkable achievements during the first Annual Assembly in Bertinoro -Italy- on the 15th of September 2009.
CTK pro tempore board established by Martina Contin — last modified 2009-10-09 14:27
Following a first preparatory meeting in Heidelberg (DE), a group of researchers representing some of the most advanced open source initiatives in the area of medical imaging and modelling met in Oxford (UK) on 25th September 2009 to join forces in a new open source project called “Common Tool Kit” that could rapidly become the most important software resource worldwide in the domain of biomedical visualisation and computing.
VPHOP presented at Bioengineering ’09. by Martina Contin — last modified 2009-10-09 15:16
The second conference and exhibition of the Society of Bioengineering (Bioengineering ’09), held on September 24th-25th 2009 in Oxford-Keble College, saw as invited keynote speaker Marco Viceconti, Coordinator of the VPHOP integrated project. Dr. Viceconti presented the current state of the art in multiscale modelling of the musculoskeletal system, including some recent results produced by the VPHOP consortium.
VPH represented at the first Consultation meeting on eHealth ELSA by Martina Contin — last modified 2009-10-23 14:34
With the communication COM(2009)116 of 13 March 2009 "A Strategy for ICT R&D and Innovation in Europe: Raising the Game", the European Commission started a consultation process that could lead by 2014 to the launch of a European Large Scale Action (ELSA) on Electronic Health (eHealth). A number of key figures in the VPH community were invited to attend the first formal consultation meeting on 29 September 2009 in Brussels.
VPH at MICCAI2009 by Martina Contin — last modified 2009-10-23 15:18
As part of the important conference MICCAI2009, held in London on September 2009, Gábor Székely (ETH Zurich) organised a one-day tutorial on physiological modelling. The event, which saw the participation as invited speakers of various members of the VPH NoE, was well attended and well received by the participants.
First VPHOP annual meeting by Martina Contin — last modified 2009-11-06 12:03
The VPHOP international consortium, which aims to develop the next-generation technology for the diagnosis, prognosis, and treatment planning of osteoporotic fractures, has just gathered in occasion of first project general assembly in Bertinoro (Italy).
Innovative VPHOP technology assessment method presented at the ICCB in Bertinoro-Italy by Martina Contin — last modified 2009-11-06 11:46
Member of the VPHOP consortium, Rainer Thiel, presented the VPHOP technology assessment model during the IV International Conference on Computational Bioengineering (ICCB2009), Bertinoro in date September 16-18, 2009. VPHOP not only validates its technologies technically, but also assesses patient-based and societal socio-economic benefits, costs, and risks.
Kaiser Permanente’s meaningful use of its EHR by Martina Contin — last modified 2009-11-19 17:19
As the Office of the National Coordinator for Health IT continues to hone its definition of meaningful use for health IT, it should take note of the results of Kaiser Permanente’s osteoporosis prevention program.
"... a good beginning makes a good ending!": VPHOP successfully passed its first annual review by Martina Contin — last modified 2009-11-26 14:18
On November 10th, 2009 the VPHOP project had its first year of activity reviewed by the European commission. The comments of the panel of international experts that reviewed the project activity were really positive and gratifying, underlining the excellent progress made so far by the consortium.
FP7-ICT-2009-6 has been released! by Martina Contin — last modified 2009-11-27 12:29
Call 6 for Information and Communication Technologies has just been launched.
Sign the petition for the VPH Institute by Martina Contin — last modified 2010-01-08 21:06
It is time to give the VPH community a collective identity that is persistent and that can speak with one voice when necessary. We invite you to sign the public petition for the creation of a European "Virtual Physiological Human (VPH) Institute".
QResearch produces new fracture risk score by Martina Contin — last modified 2009-12-11 17:48
A simple new score which can predict the risk of patients suffering fractured bones due to osteoporosis has been developed using the QResearch database. The algorithm, QFractureScores, can be used by clinicians and patients and calculates an individual's percentage risk of an osteoporotic fracture over the next ten years, allowing early intervention to take place.
ICCB2009: download the proceedings on-line by Martina Contin — last modified 2009-12-16 01:01
The book of abstract of the IV International Congress on Computational Bioengineering has been published on-line and is now available to be downloaded.
VPH Institute: sign the support petition by Martina Contin — last modified 2009-12-16 15:06
The creation of the VPH Insitute is now in process. Give your support to this initiative.
NICE established a new programme to evaluate medical technologies by Martina Contin — last modified 2009-12-15 18:20
The National Institute for Health and Clinical Excellence is launching a new programme focusing specifically on the evaluation of innovative medical technologies (including devices and diagnostics). This new programme will both compliment and operate in conjunction with NICE’s existing technology appraisal capacity, which will continue to evaluate new pharmaceutical and biotechnology products.
Model Reproducibility for Physiome Research and the VPH Institute by Martina Contin — last modified 2010-01-11 11:41
If you are involved in VPH research we need your help and support! Please look at the following news items which are petitions based on a Model Reproducibility statement and the creation of the VPH institute.
International Summer School on Biomedical Imaging by Martina Contin — last modified 2010-01-18 18:13
9th IEEE EMBS (International summer school on biomedical imaging) Berder Island, France, 18-26 June, 2010
VPH Presented at the medical simulation community by Martina Contin — last modified 2010-02-01 17:19
The SSH/ISBMS 2010 meeting in Phoenix, AZ, included a keynote plenary presentation dedicated to the Virtual Physiological Human. The talk, given by Marco Viceconti, Outreach Program responsible for the VPH Network of Excellence, presented the scope, vision, and the current development of the VPH initiative. This presentation targets one of the research communities, that of simulation in healthcare, which is considered neighbourhood domain for the VPH initiative. The high interest the presentation received confirmed that simulation in healthcare training, planning, and provision is a natural target application for VPH technologies.
Military asked to resume 3D human body mapping technology by Martina Contin — last modified 2010-06-04 13:46
A medical advisor to the U.S. military is urging the government to support the development of modeling technologies in order to create advanced computer simulations of the human body.
ICT 2010: Call for Exhibit Proposals by Martina Contin — last modified 2010-03-02 16:48
The ICT 2010 Exhibition will cover, in over 5000 square meters, Europe's latest cutting edge ICT research results. The aim of the exhibition is to showcase the latest work and concrete results in upstream ICT as well as close-to-market projects.
OpenSim 2.0 has just been released by Martina Contin — last modified 2010-03-05 10:57
The OpenSim software is now freely available to the biomechanics research community and enables computer modeling and simulation of human and animal movement.
'Virtual cell' could bring benefits of simulation to biology by Martina Contin — last modified 2010-03-12 13:46
Markus Covert is close to completing a computer model of the microbe Mycoplasma genitalia, a sexually-trasnmitted parasite. The bug is ideal for virtual re-creation because of its simplicity: only 521 coding regions.
Declaration to simplify European Research Funding by Martina Contin — last modified 2010-03-12 13:48
Do you agree that the administrative burden and the financial regulation of European research funding should be simplified? Sign this declaration and invite others to join!
First VPH Conference from 30th September to 1st October 2010: call for papers by Martina Contin — last modified 2010-03-12 13:47
The Virtual Physiological Human Network of Excellence (VPH NoE) will hold the first of a series of VPH Conferences (VPH2010) on 30th September to 1st October, 2010. The first meeting will be held in Brussels, Belgium, and is supported by the European Commission ICT for Health / DG Information Society and Media
VPHOP gets international: NMS Physiome kicks-off by Martina Contin — last modified 2010-03-12 13:45
Neuro-Musculo-Skeletal Physiome, or NMS Physiome for short, officially started on January 27th, 2010. This is a VPH Internationalisation cooperation project between the European integrated project VPHOP, and the United States NIH Center for physics-based Simulation of Biological Structures, SIMBIOS.
OpenSim workshop April 28-30, Stanford University by Masinara — last modified 2010-04-07 16:50
The Stanford University will hold the next OpenSim workshop from April 28 to 30. The three-days workshop is intended for advanced users who want to work directly with the OpenSim staff on specific research projects.
V International Congress on Computational Bioengineering by Masinara — last modified 2010-04-07 16:41
The ICCB2011 will be held from 9 to 11 November, 2011 in Mazatlan, Mexico. The International Congress on Computational Bioengineering is organized every two years to promote scientific exchange and to foster academic collaboration in several areas related with Computational Bioengineering in academic and other applied research environments.
VPHOP News by Marco Viceconti — last modified 2010-03-26 07:38
This is the billboard where you can read the News produced by the VPHOP project.
New PMMA formulation invented by Masinara — last modified 2010-04-07 16:39
The Angstrom laboratory, belonging to Uppsala University, invented a PMMA formulation with controllable porosity for optimisation of mechanical properties (e.g. stiffness closer to adjacent bone) and slow release of active ingredients (e.g. antibiotics). The patent application for a new PMMA bone cement partly falls under the VPHOP project.
New algorithm of mesh morphing presented at ISS workshop by Masinara — last modified 2010-04-07 16:39
A novel algorithm of mesh morphing for the rapid generation of finite element models of human femoral anatomies, developed by IOR and Ansys France within the VPHOP project was presented by the IOR researcher Lorenzo Grassi during the Third International OPV-MNVT Slide reading workshop.
VPHOP Satellite Symposium Agenda, May 5th, Florence Italy by Masinara — last modified 2010-04-29 11:19
The VPHOP Consortium organizes a symposium entitled “Assessing fracture risk: the future for designing new therapies” which will be held during the IOF WCO-ECCEO10 Congress in Florence, Italy. The symposium will take place on Wednesday May 5th from 14:00 to 15:30, in Hall B, Spadolini Pavillion – Fortezza da Basso, Viale Filippo Strozzi 1. The event will provide an opportunity to present the clinical community the early results of the VPHOP project on the new technology to fight osteoprosis.
VPHOP Mid-year results by Masinara — last modified 2010-05-10 14:12
The mid-year progress report was submitted to the European Commission accordingly with the timetable. This 100-pages document describes the large amount of activities carried out in the third semester of the project from all the VPHOP Partners. Almost every contractual output was completed on time. The EC reviewers will analyse it in the following months and they will give us their feedback.
VPHOP International Clinical Committee meets by Marco Viceconti — last modified 2010-05-10 15:01
In order to keep the focus of the VPHOP project as close as possible to the true needs of the clinical world was formed an advisory clinical committee composed by three of the most prestigious clinical experts in osteoporosis worldwide, in addition to the four clinical partners of the project. This clinical committe has now met for the first time in Firenze, during the Wolrd Congress of Osteoporosis.
New HPC facilities available for VPHOP consortium by Debora Testi — last modified 2010-05-10 15:00
The previous BCX machine used for the project has been recently substitute with a new IBM cluster which is available for use to VPHOP partners.
OpenClinica interface by Debora Testi — last modified 2010-05-10 14:56
In order to collect patients’ information at the project clinical centres a web-based application has been established on the OpenClinica framework.
VPHOP gets coverage on Biomedical Computation Review by Masinara — last modified 2012-04-23 11:30
The summer issue of Biomedical Computation Review, a quarterly journal published by the national Center for Biomedical Computing at Stanford, covers the topic of physiome research.
VPHOP begins clinical assessment: preparations for trial set up successfully concluded by Masinara — last modified 2010-05-21 07:59
Formally closing the preparations for the clinical assessment of the VPHOP technologies, the VPHOP validation framework and clinical set-up report has now been released. With the infrastructure and a joint clinical protocol in place, the VPHOP clinical partner institutions have started to enrol patients for the VPHOP clinical trials.
Darcy rheological model for biomaterial flow simulation by Masinara — last modified 2010-06-04 11:43
The VPHOP project developed a computational model which describes the flow of biomaterials in porous bone structures by considering the region-dependent porosity of the bone, the flow characteristics of the biomaterial and the chosen method for the filling process.
State of the art model makes its first run by Masinara — last modified 2010-06-04 14:35
In this second year of the VPHOP project, IOR in collaboration with ANSYS developed the first State-of-the-art (SOTA) probabilistic organ level model prototype implementation using a scripting language.
Special issue of the Philosophical Transactions covers VPHOP research by Masinara — last modified 2010-06-04 13:44
Three papers from the VPHOP consortium are included in June 2010 issues of Philosophical Transactions of the Royal Society Part A: Mathematical, Physical and Engineering Sciences. Part I and II of "The virtual physiological human: computer simulation for integrative biomedicine" are now available on-line.
Latest news on VPHOP Satellite Symposium in Florence by Masinara — last modified 2010-05-24 07:00
More than 400 qualified clinical experts from all over the world met at what is currently the most important clinical appointment on Osteoporosis worldwide to discuss preliminary results and strategic objectives of the VPHOP project. The VPHOP satellite symposium was held as part of the IOF World Congress on Osteoporosis & 10th European Congress on Clinical and Economic Aspects of Osteoporosis and Osteoarthritis, organized by the International Osteoporosis Foundation the largest global non governmental organization dedicated to the prevention, diagnosis and treatment of osteoporosis.
Two funding opportunities with OBSSR by Masinara — last modified 2010-06-12 09:03
The U.S. Department of Health and Human Services, Office of Behavioral and Social Sciences Research, is issuing these two founding announcements (FOAs) for basic research on social network analysis and multidisciplinary research on mechanistic links between psycosocial stress and health in aging.
CellML repository curates some key published models of bone remodelling by Masinara — last modified 2010-06-30 11:35
As part of the international collaboration between the VPHOP project and the University of Auckland, the CellML repository makes now available some published models of bone adaptation.
VII European International Congress "Healthy and Active Ageing for all Europeans II" by Masinara — last modified 2010-06-23 10:07
Providing a unique opportunity for scientific interdisciplinary dialogue among researchers, practitioners and professionals working with older person in a vast array of sciences, this congress will be held in Bologna, Italy, from 14th to 17th of April, 2011.
Quantitative Systems Immunology Summer School by Masinara — last modified 2010-07-01 12:06
Duke University is hosting an immune modeling summer school form 19 to 23 July in San Antonio, Texas. The registration deadline for this event is the 1st of July.
Clinical trials to assess the VPHOP technology started by Masinara — last modified 2010-07-02 11:40
The clinical data collection started this month in three (UGE, CHA and IOR) of the four partner hospitals. Each centre enrols about 40 patients who are undergoing the VPHOP clinical data collection protocol. The protocol consists of exams like questionnaire, DXA, fasting blood samples, physical activity tests and additional optional radiographic exams like CTs. The data collected will be used to assess the value of the VPHOP technology by the end of August 2011.
VPHOP study on evaluation of strains in the human femur has been presented at the ESB2010 by Masinara — last modified 2010-08-31 09:23
The study "Evaluation of strains in the human femur with Meshless Cell Method: comparison with FE models and experimental measurements" compiled by Pani M., Schileo E., Taddei F., Viceconti M., has been presented during the Bone Imaging & Computation session at the ESB2010 congress which took place from 5 to 8 July in Edinburgh, covering the traditional core topics of the European Society of Biomechanics while including emerging areas in which much new and exciting biomechanics research is taking place.
VPHOP technology assessment method presented at the HTAi in Dublin/Ireland by Masinara — last modified 2010-07-15 15:25
VPHOP consortium partner EMPIRICA presented the VPHOP technology assessment model at the 7th Annual Meeting of Health Technology Assessment International, 6th - 9th June 2010, in Dublin, Ireland. With the central theme of the conference being “How can Health Technology Assessment (HTA) resources be directed to make the greatest policy impact?”, this rapidly growing community, with 1200 attending in Dublin, gathered the leading international health economists to discuss policy, methods and international collaboration.
The VPHOP team released a study on muscle activation in sub-optimal neuromotor control conditions by Masinara — last modified 2010-08-31 09:22
The study hypothesizes that sub-optimal neuromotor control may explain a number of fractures in the elders and estimates, using a subject-specific musculoskeletal model, how the intensity of the hip load is affected by sub-optimal neuromotor controls.
SimTK Core gets released by Martina Contin — last modified 2010-09-01 12:30
SimTK Core is an open-source toolkit providing high-performance methods for biosimulations. From today it can be dowloaded from the Simtk portal.
VPHOP: a summary of the activities of the second year by Martina Contin — last modified 2010-09-24 12:02
At the end of the second year of its activities, the Osteoporotic Virtual Physiological Human –VPHOP- research project has made crucial steps upfront for the achievement of the project’s objectives. The involvement of patients, the use of advanced ICT resources and the collaboration of important clinical centres are only few of the reasons, which have made these successful accomplishments possible.
VPHOP gets coverage on the Irish Times - Science Today: "Medical avatars: mapping our health" by Martina Contin — last modified 2010-09-30 15:11
The Irish Times dedicated a full article on the VPHOP project and its personalized predictive approach. The journalist, Alison Jones, describes the Virtual Physiological Human as a computer-based avatar, which simulates the physiological reactions of someone's body, enabling to diagnose their symptoms, anticipate future illnesses and predict side-effects of treatment.
VPH - Industry Meeting 2010 by Martina Contin — last modified 2010-09-30 14:30
The event, held on 8-9 September 2010 by the Universitat Pompeu Fabra in Barcelona, was organised by the European Network of Excellence (NoE) for the Virtual Physiological Human (VPH) initiative. The aims of the meeting was to increase the awareness amongst European Industry of the vision, the concepts, and the concrete technological achievements of VPH-related research. A post-event debriefing document is now available and can be downloaded from the VPH NoE website.
The U.S. Food and Drug Administration -FDA- warns of possible femoral fractures with bisphosphonates by Martina Contin — last modified 2010-10-22 16:38
The FDA released a statement warning health care professionals and patients about the possible risk for atypical femoral fractures in patients who take bisphosphonates.
Sumbit your abstract for ISB2011 by Martina Contin — last modified 2010-11-04 18:07
The ISB2011 Organizing Committee has the pleasure to announce that abstract submissions have now started and will close on January 20th, 2011. Registration will open shortly.
University of Geneve starts patients enrollment by Martina Contin — last modified 2010-11-26 12:25
The University of Geneve, in collaboration with the NeuroZentrum Zurich, has recently started a VPHOP clinical pre-trial with 30 patients which serves to validate a set of software tools the University of Bern has developed.
Download SpineFX quarterly newsletter by Martina Contin — last modified 2010-11-30 15:04
SpineFX project is a Marie Curie Initial Training Network (ITN), focused on providing training and research in the area of spinal biomechanics and medical engineering associated with vertebral fracture. The network is composed by four leading research universities and three companies with a track record in innovation. The SpineFX ITN will deliver research in three domains; basic science, orientated research and applied research whilst focusing on three underpinning pathologies; osteoporosis, metastases and trauma. Training is provided by 'experience through research', network-wide workshops and local professional development provision.
The European Investment Bank - EIB- lends EUR 130 Million to AGFA for Healthcare R&D Projects in Belgium, Germany, Austria and France by Martina Contin — last modified 2010-11-30 16:04
EIB is lending EUR 130 million to finance the research, development and innovation (RDI) projects in healthcare IT & imaging technology of the Agfa Group. These strategic projects for Agfa HealthCare aim to increase both the efficiency of healthcare and the quality of services for patients. By financing these projects, the EIB will also foster the competitiveness of European technologies and contribute to the European Union's objective of developing Europe's knowledge economy.
Special Issue on Medical Imaging in Computational Physiology - IEEE Transactions on Medical Imaging by Martina Contin — last modified 2010-11-30 16:34
We invite submission of papers describing new methods and tools for image-based approaches to the VPH/Physiome. The special issue will give particular attention to contributions describing methods and tools combined with a thorough clinical evaluation.
Artisynth Biomechanical Modeling Team from University of British Columbia Seeking Partners by Martina Contin — last modified 2010-12-23 13:11
The Artisynth biomechanical modeling project (, University of British Columbia, Canada) is seeking research partners to help create anatomical models using our new multibody/FEM software, or to exploit our existing models of human oral and upper airway anatomy to develop research and medical applications involving this region.
Call for papers for IEEE TBME Letters by Martina Contin — last modified 2011-01-04 15:10
IEEE Transactions on Biomedical Engineering (TBME) is pleased to announce its Special Issue of TBME LETTERS on “Multi-scale Modeling and Analysis for Computational Biology and Medicine” scheduled for publication in September/October 2011.
First prototype of the VPHOP hypermodelling technology by Martina Contin — last modified 2011-02-03 07:01
The VPHOP project has recently investigated the best technology to be used in the development of the hypermodel architecture. Three different technologies have been evaluated to select the potential candidate for the hypermodel implementation. Among the others, the MAF implementation has been identified as the most appropriate for the VPHOP hypermodel and will be used for the further implementation phase with integration of relevant part of the ESB technologies.
First results of the VPHOP hypermodel prototype of the femoral region to predict the risk of fracture by Martina Contin — last modified 2011-02-03 06:58
The first hypermodel prototype recently developed by researchers at the Istituto Ortopedico Rizzoli is a finite element model of the proximal femur anatomical region that can handle probabilistic descriptions of all input variables and gives as output a probabilistic description of the fracture risk.
First technology impact assessment of VPHOP produces promising results by Martina Contin — last modified 2011-02-03 16:03
The central aim of VPHOP is to improve the current management of osteoporosis by predicting the risk of bone fracture much more accurately than presently possible. For impacting on the clinical practice, research and development of the predictive technologies alone will not suffice; therefore VPHOP also ensures the provision of empirical evidence about the clinical and socio-economic benefits. Project partner Empirica, in collaboration with Istituto Ortopedico Rizzoli -IOR- and the VPHOP consortium, has recently completed the first annual VPHOP technology assessment. The preliminary cost-benefit analysis substantiates that VPHOP technologies, when incorporated in the design of future clinical pathways for osteoporosis, can fulfil the Virtual Physiological Human -VPH- promises of reducing costs and improving the quality of care for European health systems.
The VPHOP integrated project successfully pass the second annual review by astagni — last modified 2011-02-28 14:34
On January 26th a panel of five international experts reviewed the second year of activities of the VPHOP project. In the Technical Review Report the reviewers' panel acknowledge the very good progress made by the project Consortium, as well as the high scientific quality of work done so far. They also recognise that the integration of all components into a complete integrative model will require an even stronger collaboration within the consortium.
eHealth Strategies study results: Summary report and country reports on eHealth progress in Europe by astagni — last modified 2011-03-31 15:54
The European Commission sponsored the eHealth Strategies study "European countries on their journey towards national eHealth infrastructures - evidence of progress and recommendations for cooperative actions". It is now available an online version of this report, while the full report will be published in Spring 2011. In addition, more than 30 individual reports detailing policy actions and deployment of eHealth applications in Member States and other European countries are available at the study website as well.
Fast FE-solver for nonlinear analyses: a VPHOP deliverable completed by astagni — last modified 2011-03-31 15:55
On the 21st of January 2011 the deliverable 6.2 of the VPHOP project has been completed. Deliverable D6.2 aimed at the testing and further development of two Finite Element (FE) solvers (ParFEnl and Ansys) for very large non-linear finite element problems such as they occur when analyzing the micro-architecture of cancellous bone. It was found that both solvers performed well on the PLX supercomputer system, with good scaling characteristics. Both codes were also able to simulate the failure process up-to failure load ranges (deformations around 2%), even for test problems with on the order of millions of elements, in acceptable amounts of cpu-time.
ICCB 2013: call for bids by astagni — last modified 2011-03-31 15:53
The International Conference on Computational Bioengineering (ICCB) opened a public call for bids to host the 2013 issue, ICCB 2013.
Actibelt technology offers activity profile of patients by astagni — last modified 2011-04-01 15:52
Another deliverable of the VPHOP Project has been completed. Deliverable D3.2 aimed to provide an analysis of the motion data collected using the actibelt® technology to determine the activity profile of patients tested at the Charité - Universitätsmedizin Berlin. In addition, quantitative measures for providing an objective assessment of subject stability from rapid clinical trials have also been investigated.
Prof. Prendergast elected new Provost of Trinity College by Valeria Codeluppi — last modified 2011-05-09 08:19
Professor of Bio-Engineering and Vice Provost at Trinity College Dublin, Professor Patrick Prendergast, has been elected Provost of Irelands most prestigious university.
“Non-Destructive High Resolution X-Ray Micro-CT and Live Animal Imaging Workshop” in Adelaide, South Australia, Australia by Martina Contin — last modified 2011-05-04 09:58
Monday and Tuesday 2-3 May 2011 a "Non-Destructive High Resolution X-Ray Microtomography and Live Animal Imaging" workshop was held at Adelaide Microscopy, (Adelaide, South Australia, Australia). The guest speakers of the event were: Allan Jones (Australian Centre for Microscopy and Microanalysis, University of Sydney), Ian Parkinson, Egon Perilli (Bone & Joint Research Laboratory, SA Pathology, Adelaide; and The University of Adelaide), Agatha Labrinidis (The University of Adelaide).
Frax assessment of osteoporotic fracture probability by Valeria Codeluppi — last modified 2011-05-09 16:00
In the VPHOP project we are trying to revolutionize the diagnosis and treatment of osteoporosis. But before we can improve something, it is good to know how is something done currently. So we asked our clinical leader, Prof. René Rizzoli, to write a brief explanation of what is the current standard of care for osteoporosis.
EOS imaging: the clinical study is ready to start by Valeria Codeluppi — last modified 2012-04-23 11:22
On the 23rd of March in Paris it was held an important meeting for the VPHOP project which saw the partecipation of representatives of Arts Association (LBM), EOS imaging (BSP), Institut National de la Santé et de la Recherche Médicale (INS) and Istituto Ortopedico Rizzoli (IOR). The Partners made the point on the clinical study which will have to be performed on 5-10 patients and on the development of specific vertebra and femur organ models derived from data obtained with the new EOS software for dual-energy X-Ray imaging.
VPHOP board made important steps for the future of the project by Valeria Codeluppi — last modified 2012-04-23 11:20
During the last Board meeting of the VPHOP Project held in Bologna on 13th of April, all Board members together with some other representatives of the Board Partners discussed about the status of the project and made strategic plans for the activities of the next years.
WP7 model update: definition of the pre and post augmentation vertebral model by Valeria Codeluppi — last modified 2012-04-23 11:19
As a part of WP7, the University of Bern is currently testing routines that update the material properties of pre-treatment FE hyper models, to simulate the influence of cement augmentation.
Statistical modeling of human femurs succesfully tested by IOR by Valeria Codeluppi — last modified 2012-04-23 11:16
The development and validation of algorithms for statistical modeling of shape and mineral density (BMD) of human femurs have now been completed with good results
High resolution imaging in-vivo at the hip and spine by Valeria Codeluppi — last modified 2012-04-23 11:14
The use of a new high-resolution imaging technique for the hip and spine were explored (flat-panel CT system - Philips XperCT). It was found that some structural parameters could be accurately determined for bone in-vivo. VPHOP studies at UGE Partner.
VPH ARGOS POLICY BRIEF: final public draft by Valeria Codeluppi — last modified 2011-06-06 17:23
After the ARGOS Finale Meeting held on 11th May 2011 in Budapest, the final public draft of the ARGOS VPH Policy Brief has been released. The document recommends governments of the European Union and the United States of America to support the establishment of a permanent International Multistakeholder Advisory Group (VPH/MAG) as a first step towards the creation of a transatlantic VPH Cyberinfrastructure, a global infrostructure that will integrate all digital infrastructures that share data, information, or models relative to biomedicine.
A new GPU powered system in CINECA (upgrade of PLX) by Debora Testi — last modified 2012-04-23 11:10
CINECA and SCS are announcing a very important upgrade of PLX system which reaches now a peak performance near to 300 TFlops, making it the most powerful Supercomputer in Italy.
VPHOP development model: the eXtreme Programming approach by Debora Testi — last modified 2012-04-23 10:44
Based on previous long and successful experience in collaborative software implementation of partners SCS, BED, and IOR, the VPHOP software tools will be implemented following the eXtreme Programming (XP) management approach which relies on short-term software releases and high involvement of the end-users in the development process.
First prototype of morphable musculoskeletal model released by Valeria Codeluppi — last modified 2012-04-20 16:58
Deliverable D10.1 released: At PM32, WP10 partners delivered the first prototype for wrapping a set of muscles under leg movement that enforces volume conservation and prevents inter-penetration between models representing individual muscles and the skeleton.
VPHOP completes the specifications for the hypermodelling technology by Valeria Codeluppi — last modified 2012-04-23 11:07
The end of this month marks the closure of three important deliverables. In “D4.4: Specification for diagnosis application” the consortium provides the specifications for all the applications used by the clinicians, except those for the interventional treatment planning, which are provided in “D7.2: Specifications for intervention application”.
Model validation: in vitro testing of intact and augmented vertebras by Valeria Codeluppi — last modified 2012-04-20 16:55
Procedures were developed at IOR for in vitro mechanical testing of intact and augmented vertebral bodies. Bone strain, stiffness and load to failure are measured.
VPHOP Participants' contact information by Valeria Codeluppi — last modified 2012-04-20 16:54
Database wrapper to update the staff and the person months of your partners.
VPHOP towards end-user applications by Valeria Codeluppi — last modified 2012-04-20 16:54
The PMO has recently submitted to the EC Project Officer a non-contractual document named "D1.101 Use cases and architectural paradigm". This document, not planned by contract, is the result of a discussion that involved all VPHOP Partners and aims to describe how VPHOP technology will be translated into end-user applications. This document is now available for the whole Biomedical Community to be consulted.
VPHOP Workshop Application accepted by ORS by Valeria Codeluppi — last modified 2012-04-20 16:53
The ORS (Orthopaedic Research Society) program committee has accepted the application for the organisation of a VPHOP workshop in occasion of the ORS 2012 Annual Meeting which will be held in San Francisco, California, February 4-7 2012.
VPHOP 3rd Annual Consortium Meeting by Valeria Codeluppi — last modified 2012-04-23 10:57
Thanks to the kind offer of Keita Ito, WP6 leader, the 3rd Annual Consortium Meeting will be hosted by the Technische Universiteit Eindhoven - TU/e. The meeting will last two days, from Monday 14th to Tuesday 15th of November 2011.
Deliverable "D3.3 Range of functional metrics for each subject in the three subject Cohorts" has been fully accomplished by Valeria Codeluppi — last modified 2012-04-20 16:52
This deliverable aims to quantify a number of functional metrics for each subject evaluated within WP3 that are associated with differences in musculoskeletal loading or a subject’s propensity to stumble or fall.
Deliverable "D4.3 Second hypermodel prototype" has been fully accomplished by Valeria Codeluppi — last modified 2012-04-20 16:52
In this deliverable it is described the structure of the second Hypermodel prototype of the vertebral region, still using the available state-of-the art sub-models.
Deliverable "D6.3 Bone Micro-Architecture Database" has been fully accomplished by Valeria Codeluppi — last modified 2012-04-20 16:51
The main goal of WP6 is to provide patient-specific tissue-level micro-architecture and continuum-level mechanical properties for the diagnosis and prognosis of bone fracture risk.
Deliverable "D6.4 Specification for prognosis application" has been fully accomplished by Valeria Codeluppi — last modified 2012-04-20 16:51
This deliverable describes how WP6 will use this database to provide patient-specific continuum models and describes the interactions with the other WP's involved.
First densitometry results with the EOS dual-energy prototype by Valeria Codeluppi — last modified 2012-04-23 11:08
The EOS dual-energy prototype aimed at densitometry studies has been successfully installed at the Lyon site and has provided its first results.
In Vitro Experiments completed at IOR for Augmentation Model Validation by Valeria Codeluppi — last modified 2012-04-23 11:05
Together with the University of Bern, in vitro experiments were completed at the Istituto Ortopedico Rizzoli to provide validation data for the interventional treatment planning modules.
Deliverable "D2.3 Complete version of the collaborative environment" has been fully accomplished by Valeria Codeluppi — last modified 2012-04-23 11:02
The deliverable is the description of the final collaborative environment deployed at the end of the third year of the project.
VPHOP 3rd Annual Consortium Meeting Final Agenda and Participants by Valeria Codeluppi — last modified 2012-04-23 11:01
It's time for the 3rd VPHOP Annual Meeting hosted by the Technische Universiteit Eindhoven from Monday 14th to Tuesday 15th of November 2011.
Dr. Friederike Schulte was awarded with the ETH Medal for Outstanding Doctoral Thesis by Valeria Codeluppi — last modified 2012-04-23 11:01
The ETH Medal is given every year to the 8% best theses awarded at ETH Zurich. Schulte will receive a Certificate and the Medal from the Rector in an official ceremony on 13 January 2012 together with all the other medalists.
VPHOP abstract accepted for presentation at ECR2012 Imagine workshop by Valeria Codeluppi — last modified 2012-04-23 10:59
The abstract “Image-based, personalised and multiscale modelling to predict the risk of fracture in osteoporotic patients: the VPHOP integrated project” was one of the 18th selected (from a total of 85 submitted abstracts!) to participate to the “Novel technology that shapes Radiology: EIBIR presents IMAGINE” workshop which will be held during the ECR 2012 in Vienna.
Deliverable "D2.4 Digital Library services final release" has been fully accomplished by Valeria Codeluppi — last modified 2012-04-23 10:59
This document describes the last features of the PhysiomeSpace service and how the storage service will be used in the hypermodel technology architecture.
Deliverable "D7.3 Final constituents-based failure criteria model" has been fully accomplished by Valeria Codeluppi — last modified 2012-04-23 10:58
This report describes the development,validation and testing of the final constituents-based failure criteria model for bone-cement composites which is an essential deliverable for the VPHOP Intervention Application.
Deliverable "D8.3 Annual report on ethical, legal and privacy issues (2011)" has been fully accomplished by Valeria Codeluppi — last modified 2012-04-23 10:57
This 2011 report mainly reports on patient data exchanged between partner for the period October 31, 2010 through October 31, 2011.
Deliverable "D9.3b Annual socio-economic and technology assessment report (2011)" has been fully accomplished by Valeria Codeluppi — last modified 2012-04-23 10:55
This deliverable develops upon the intermediate results achieved during the initial project phase, and updates the earlier results of the impact assessment performed during the second year of the project.
Deliverable "D3.6 Patient-specific probabilistic model of skeletal overloading" has been fully accomplished by Valeria Codeluppi — last modified 2012-06-28 10:23
This deliverable aims to provide a patient-specific probabilistic model of skeletal overloading for each subject evaluated within WP3 that are associated with differences in musculoskeletal loading or a subject’s propensity to stumble or fall.
Deliverable "D6.5 Final tissue properties model" has been fully accomplished by Valeria Codeluppi — last modified 2012-04-23 10:53
This deliverable describes the constitutive equations that will be used to describe the material properties of bone in the hypermodel.
VPHOP 3rd Review Meeting Final Agenda by Valeria Codeluppi — last modified 2012-04-23 10:52
It's time for the 3rd VPHOP Review Meeting hosted by SCS Super Computing Centre (Bologna, Italy) from Monday 16th to Tuesday 17th of January 2012.
VPHOP 3rd Review Meeting: green light from the EC reviewers by Valeria Codeluppi — last modified 2012-04-23 10:52
The third Review Meeting was held in Bologna last 16th-17th of January in front of the EC project officer Joel Bacquet and four peer scientists EC reviewers. In these the two days some representatives of VPHOP Consortium showed the results of the third year project and answered the reviewers’ questions. At the end of the meeting Mr. Bacquet communicated that the reviewers are satisfied by the project outcomes achieved so far and that the activities must continue to complete all the project goals by the end of this fourth year.
VPHOP hits 1 millions computation hours on PLX! by Debora Testi — last modified 2012-04-23 10:51
In the last year, the VPHOP partners have performed a huge number of simulations on the PLX system hosted at CINECA. In all 2011, the number of computing hours associated to VPHOP users has been of about 1 million!!!
VPHOP at ORS 2012 and ECR 2012: great success! by Valeria Codeluppi — last modified 2012-04-23 10:51
The last month was very busy for the VPHOP Consortium. The partners has continued to disseminate the vision and the early results of the project to different research and clinical communities.
VPHOP: The 3rd Year Outcome Report by the EC Reviewers by Valeria Codeluppi — last modified 2012-04-23 10:50
The outcome of the third review meeting held in Bologna on 16th-17th January has been presented in a consolidated review report received by the PMO at the beginning of February.
The first version of the final Hypermodel run successfully on the PLX platform. by Valeria Codeluppi — last modified 2012-04-23 10:50
The first version of the Hypermodel of the femoral region, originally due for PM38, but postponed to PM42, was successfully built integrating all five sub-models operating at different dimensional scales and successfully run on PLX platform.
Empirica Webinar on Assessing Clinical and Economic Benefits of Biocomputational Models- A Case Study with Physiome Models by Valeria Codeluppi — last modified 2012-04-23 10:31
In March, Empirica researchers Dr. Karl Stroetmann and Dr. Rainer Thiel presented a webinar on the validation of Virtual Physiological Human (VPH) simulation models and the assessment of their potential clinical and socio-economic impact on both society and individual stakeholders like clinicians.
VPHOP Scientific Publications has reached 116! by Valeria Codeluppi — last modified 2012-04-23 10:48
At the end of the 3rd Year of the project, the number of Scientific Publications published by the VPHOP Consortium is now more than 100.
Actibelt “Balance App” available for Android platforms by Valeria Codeluppi — last modified 2012-05-07 15:49
VPHOP Partner "SLCMSR - The Human Motion Institute together with Trium Analysis Online GmbH" has built, tested and presented a fully automatic actibelt app for android.
Delivered in vitro data for validation within WP6 and WP7 by Valeria Codeluppi — last modified 2012-04-30 11:03
IOR has completed the data processing of the in vitro data (bone strain, stiffness and load to failure) of the vertebrae and femurs involved in the validation tasks within WP6 and WP7
VPHOP Project Board in Munich by Valeria Codeluppi — last modified 2012-05-07 16:03
Before the final semester of the project, the VPHOP Board will meet in Munich next June, the14th, 2012
Bone loading estimation in the human distal radius by Valeria Codeluppi — last modified 2012-05-23 16:56
High-resolution imaging and bone remodelling simulations would allow to simulate how diseases or treatments affect the bone morphology, but require the definition of physiological loading conditions. Here we show that it is possible to estimate realistic loading in the distal human radius from the bone micro-architecture and therefore provide boundary conditions for such simulations.
XPM can really improve research projects by Valeria Codeluppi — last modified 2012-06-05 08:51
XPM was adopted in VPHOP from the beginning. This news wants to explain again what it is, how it was applied and how it can be improved and deployed in future projects.
First fibre-based musculoskeletal model available. by Valeria Codeluppi — last modified 2012-06-05 08:55
In April/May 2012, WP10 reached the milestone M10.1 by making the last technique for fibre-based musculoskeletal model available.
VPHOP YR2012 Project Public Presentation and Video by Valeria Codeluppi — last modified 2012-06-04 17:09
The outcomes of the 4th year of the project are presented in the Project Public Presentation.
Deliverable "D5.4 Multiscale models to predict bone modelling and remodelling" has been fully accomplished by Valeria Codeluppi — last modified 2012-07-06 15:42
The aim of WP5 is to produce a computational model of bone modelling and remodelling which is able to predict changes in bone morphometry in response to aging, disease (osteoporosis) and associated treatments. In this deliverable it is presented the validation studies performed to deliver the final bone remodelling model.
Deliverable "D7.4 Patient specific interventional treatment planning and guidance" has been fully accomplished by Valeria Codeluppi — last modified 2012-07-06 15:48
This deliverable describes the development and implementation of the graphical user interface (GUI) of the interventional application for bone augmentation.
Towards population based modelling (and a better characterisation of bones) by Valeria Codeluppi — last modified 2012-07-06 15:57
Within VPHOP, Ansys and IOR analysed large bone populations, and developed an effective tool to univocally characterise the complexity of bone shape and tissue density distribution.
Vertebral fragility in patients with prevalent fracture by Valeria Codeluppi — last modified 2012-07-06 15:41
Four clinical centers participated in the data collection for the clinical validation of the technologies developed in the frame of the VPHOP project: University Hospital of Charité in Berlin (CHA), Rizzoli Orthopedic Institute in Bologna (IOR), National Institute of Health and Medical Research in Lyon (INS) and University of Geneva (UGE).
Patient-specific bone cements: the results by Uppsala University by Valeria Codeluppi — last modified 2012-07-06 15:42
Osteoporotic patients demonstrate a large variation in bone quality, and hence in bone mechanical properties.
VPHOP at Mellanby Centre Research Day (Sheffield,UK) and at CIMA Seminar (Liverpool, UK) by Valeria Codeluppi — last modified 2012-08-03 16:24
VPHOP coordinator attended the 3rd Annual Mellanby Centre Research Day last 21 June 2012 in Sheffield (UK) and was also invited to the CIMA Seminar at the University of Liverpool on 11st July 2012. In both occasions he presented the results of the VPHOP project.
VPHOP hypermodel technology: the programmable wrapper by Debora Testi — last modified 2012-07-31 11:23
SCS recently added a new component to the hypermodel technology of the VPHOP project which allows reserachers not only to expose its algorithms and model to the infrastructure but also to easily modify or update the code to be executed. This gives researchers much more flexibility in the developement and testing of new workflows.
VPHOP workshop at VPH2012 by Martina Contin — last modified 2012-08-03 16:18
A dedicated workshop on VPHOP will take place at the VPH2012 conference on Sept 19th, 2012 in London. Join us to discover the VPHOP technologies!
PhysiomeSpace increased security! by Debora Testi — last modified 2013-01-08 12:08
Thanks to work done within the VPHOP project, an upgraded version of PhysiomeSpace is now released with important new features: increased performances and security!