Foster City, CA, 3rd April, 2008. The U.S. Patent and Trademark Office has granted U.S. Patent "Method and Apparatus for Computer Modeling Diabets" to Entelos, Inc, a leading life sciences company building predictive computer models of human physiology and "virtual patients" for drug discovery and development.

James Karis, President and CEO of Entelos, says: It is well known that a patient’s response to a drug depends on multiple factors, from underlying genetics to diet and lifestyle. Diabetes is even more complex, in that multiple drugs are often used to treat the disease over time. We are pleased to have this important model patent-protected to sustain our leadership position in the comprehensive in silico testing of multiple drugs and drug combinations in a highly variable virtual patient population. We intend to continue making a significant impact on this disease and on our customers’ diabetes-related programs.